The records, by study type and verdict
Growth hormone release (animal only)
The founding record, from 1998, introduces ipamorelin as a pentapeptide growth hormone secretagogue and ghrelin receptor agonist, the first selective agent of its class. In swine, rats and rat pituitary cells it released growth hormone without meaningfully raising ACTH or cortisol.
Direction: improved. Verdict: animal only. Record: PubMed 9849822.
Muscle and bone in rats (animal only)
In rats given glucocorticoids, maximum calf muscle tetanic tension and periosteal bone formation improved. Direction: improved. Verdict: animal only. Record: PubMed 11735244.
Insulin release in a dish (animal only)
In pancreatic tissue from normal and diabetic rats, insulin secretion improved in a lab dish. A dish isn't a person. Verdict: animal only. Record: PubMed 15665799.
Gut recovery after surgery in rats (animal only)
In a rat model of gut slowdown after surgery (postoperative ileus), gut transit, fecal output, food intake and body weight improved. Direction: improved. Verdict: animal only.
The one human trial that tested the same idea missed its goal. See the closed human entry. Record: PubMed 19289567.
A rat pain model (animal only)
In a rat model of visceral hypersensitivity and somatic mechanical allodynia, without active colon inflammation, measures improved. Direction: improved. Verdict: animal only. Record: PubMed 32801950.
A ferret model (mixed, animal only)
In ferrets given cisplatin, looking at weight loss and vomiting, and in isolated ferret ileum, results were mixed. Direction: mixed. Verdict: animal only. Record: PubMed 39043357.
The reviews
Reviews discuss ipamorelin among growth hormone secretagogues and among unapproved peptides. One review reports a mouse study giving ipamorelin with a second growth hormone secretagogue, with improved maximum tetanic tension, in animals only. That original study isn't in our records, and we don't name the second compound.
More on the missing approval. Records: PubMed 32257855, PubMed 41476424, PubMed 41490200.
The registrations (no result)
The registry lists two completed phase 2 ipamorelin studies for this use, NCT00672074 and NCT01280344. There's also one active, not recruiting observational study, NCT07717866.
A registration shows a study happened, not its results, so each one shows no result. The one human outcome on record is on the closed human entry.
In short: animal work and reviews, plus one human trial that missed its goal.
How did we read the record?
We use five verdicts, and no others: closed endpoint not met, animal only, no human outcome, no approved use, and not on file.
A cell gets filled only from a named record, dated with the day we read it. We read every research record here on 2026-09-05, the vendor facts on 2026-09-07, and checked the human trial identifier on 2026-09-13.
Record types are human RCT, animal, in vitro, review, registered study with no result, vendor document, and none. A row only changes when a named record changes it.
To send a correction, use the correction route.
In short: method published, corrections welcome.
About Peptara Labs
The one company we name is Peptara Labs. We only repeat what it publishes about itself, as its own statement, never as our verdict.
Who tests Peptara Labs peptides?
The certificates page names Titreon Analytical as its tester, a third-party lab whose quality system is aligned to ISO/IEC 17025:2017, not itself accredited. We keep that qualifier whole, because the short version would be false.
Does Peptara Labs publish certificates of analysis?
Yes. Its certificates are published on its certificate index, along with some bacterial endotoxin reports from a second outside lab. None of those second-lab reports covers ipamorelin, and no standalone certificate for it sits among the published lots.
What is Peptara Labs' guarantee?
Peptara Labs offers a 60 day money back guarantee on verified purity, certificate of analysis and fulfillment. It calls this a quality guarantee, never a health outcome guarantee.
In short: this comes from the supplier's own pages.
What does research framing mean here?
Every entry shows the kind of evidence behind it, and stops there. An animal or lab-dish result stays exactly that. It never becomes a result in a person. Material sold for research is described as material sold for research.
We name no benefit the record doesn't support. We give no advice, and we don't ask you to do anything.
To say it in full: we publish no instructions of any kind, no amounts, no schedules and no procedures. We read the record, and we don't tell anyone to get anything.
In short: not instructions, not advice.